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Current Prospects for the Fluoroquinolones as First-Line atomic number 65 Therapy Howard Takiff and Elba Guerrero Antimicrob. Agents Chemother. 2011, 55(12):5421. DOI: 10.1128/AAC.00695-11. Published forrad of Print 29 August 2011. These include: REFERENCES CONTENT ALERTS This scream cites 95 articles, 52 of which roll in the hay be accessed free at: hypertext transfer communications protocol://aac.asm.org/content/55/12/5421#ref-list-1 convey: RSS Feeds, eTOCs, free electronic mail alerts (when new articles cite this article), much» Information about commercial reprinting orders: hypertext transfer protocol://journals.asm.org/ spot/misc/reprints.xhtml To subscribe to to another ASM Journal go to: http://journals.asm.org/site/subscriptions/ Downloaded from http://aac.asm.org/ on November 13, 2012 by guest Updated schooling and services can be found at: http://aac.asm.org/content/55/12/5421 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Dec. 2011, p. 54215429 0066-4804/11/$12.00 inside:10.1128/AAC.00695-11 Copyright © 2011, American party for Microbiology. All Rights Reserved. Vol. 55, No.

12 MINIREVIEW Current Prospects for the Fluoroquinolones as First-Line Tuberculosis Therapy Howard Takiff* and Elba Guerrero Instituto Venezolano de Investigaciones Cientí?cas (IVIC), Caracas, Venezuela and by adding various side groups literally thousands of distinct ?uoroquinolones were synthesized. Although the increase broad-spectrum activity of cipro?oxacin (CIP) created the expectation that it would be a big-ticket(prenominal) agent against troublesom e bacteria such as staphylococcus aureus, ! unsusceptibility in these bacteria developed rapidly. Within sound a few years after the introduction of CIP, galore(postnominal) nosocomial strains (9) were resistant (10), especially Gram-positive bacteria. In contrast, CIP has remained effective much time-consuming against some enteric Gramnegative bacteria, such as Escherichia coli (49). The difference appeared to be relate to the ratio of the usual serum drug concentration to the innate MIC of the bacteria. The...If you trust to get a full essay, order it on our website: BestEssayCheap.com

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